What is questran

When used as a cholesterol-lowering agent predisposing factors for most complaints of constipation are high dose and increased age more than 60 years old.

Most instances of constipation are mild, transient and controlled with conventional therapy. Some patients require a temporary decrease in dosage or discontinuation of therapy. Rare reports of intestinal obstruction, including two deaths, have been reported in pediatric patients.

Occasional calcified material has been observed in the biliary tree, including calcification of the gallbladder, in patients to whom cholestyramine resin has been given. However, this may be a manifestation of the liver disease and not drug related. One patient experienced biliary colic on each of three occasions on which he took a cholestyramine for oral suspension product.

Other events not necessarily drug related reported in patients taking cholestyramine resin include:. GI-rectal bleeding, black stools, hemorrhoidal bleeding, bleeding from known duodenal ulcer, dysphagia, hiccups, ulcer attack, sour taste, pancreatitis, rectal pain, diverticulitis. Headache, anxiety, vertigo, dizziness, fatigue, tinnitus, syncope, drowsiness, femoral nerve pain, paresthesia. Weight loss, weight gain, increased libido, swollen glands, edema, dental bleeding, dental caries, erosion of tooth enamel, tooth discoloration.

No ill effects were reported. Should an overdosage occur, the chief potential harm would be obstruction of the gastrointestinal tract. The location of such potential obstruction, the degree of obstruction and the presence or absence of normal gut motility would determine treatment.

The recommended starting adult dose for Cholestyramine for Oral Suspension, USP powder is 1 pouch or 1 level scoopful 9 grams of Cholestyramine for Oral Suspension, USP powder contains 4 grams of anhydrous cholestyramine resin once or twice a day.

The recommended maintenance dose for Cholestyramine for Oral Suspension, USP powder is 2 to 4 pouches or scoopfuls daily 8 to 16 grams anhydrous cholestyramine resin divided into two doses. The maximum recommended daily dose is 6 pouches or scoopfuls of Cholestyramine for Oral Suspension, USP powder 24 grams of anhydrous cholestyramine resin. The suggested time of administration is at mealtime but may be modified to avoid interference with absorption of other medications. Although the recommended dosing schedule is twice daily, Cholestyramine for Oral Suspension, USP powder may be administered in 1 to 6 doses per day.

Always mix the dry powder with water or other fluids before ingesting. See Preparation Instructions. Preliminary evidence suggests that the lipid-lowering effects of cholestyramine on total and LDL-cholesterol are enhanced when combined with a HMG-CoA reductase inhibitor, e. The color of Cholestyramine for Oral Suspension, USP powder may vary somewhat from batch to batch but this variation does not affect the performance of the product.

Place the contents of one single-dose pouch or one level scoopful of Cholestyramine for Oral Suspension, USP powder in a glass or cup. Add at least 2 to 6 ounces of water or the beverage of your choice. Stir to a uniform consistency. Cholestyramine for Oral Suspension, USP powder may also be mixed with highly fluid soups or pulpy fruits with a high moisture content such as applesauce or crushed pineapple.

Cholestyramine for Oral Suspension, USP powder orange flavor is available in cartons of sixty 9 gram pouches and in cans containing grams. Effects of therapy with cholestyramine on progression of coronary arteriosclerosis: results of the NHLBI type II coronary intervention study. Circulation ; Effects on coronary artery disease of lipid-lowering diet or diet plus cholestyramine, in the St. Lancet ; National Cholesterol Education Program. Circulation Mar;89 3 : The Lipid Research Clinics Investigators.

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Rx only. Clinical Studies In a large, placebo-controlled, multi-clinic study, LRC-CPPT 1 , hypercholesterolemic subjects treated with cholestyramine resin had mean reduction in total and low-density lipoprotein cholesterol LDL-C which exceeded those for diet and placebo treatment by 7. General Chronic use of cholestyramine resin may be associated with increased bleeding tendency due to hypoprothrombinemia associated with Vitamin K deficiency. Information for Patients Inform your physician if you are pregnant or plan to become pregnant or are breast-feeding.

Laboratory Tests Serum cholesterol levels should be determined frequently during the first few months of therapy and periodically thereafter. Drug Interactions Cholestyramine resin may delay or reduce the absorption of concomitant oral medication such as phenylbutazone, warfarin, thiazide diuretics acidic or propranolol basic , as well as tetracycline, penicillin G, phenobarbital, thyroid and thyroxine preparations, estrogens and progestins and digitalis.

If this is the cause of the diarrhea, it may help. If the cause of the diarrhea is something else, Read More. Send thanks to the doctor.

Get help now: Ask doctors free Personalized answers. John Leander Po answered. No- see your doc Martin Raff answered. Diarrhea: Severe diarrhea and incontinence are not likely to be alleviated by Cholestyramine alone without a specific etiology of the GI abnormalities delineate A Verified Doctor answered. A US doctor answered Learn more.

Get a sample of stool to lab for analysis, culture. Fu with pmd. Hydrate yourself. Andres Katz answered. Be patient: Rather uncommon diarrhea after cholecystectomy is well described. Continue with current regimen and wait. Most of the times it resolves. Lomotil diph View 1 more answer.

It prevents bile acids from being reabsorbed recycled into your body, and this action can be useful in a number of different conditions. You may be prescribed colestyramine sachets to help lower the amount of cholesterol in your blood, or to reduce itching caused by a problem in your bile ducts such as primary biliary cirrhosis , or to help reduce diarrhoea caused by certain medical conditions or treatments.

When it is prescribed to lower cholesterol, by preventing the bile acids from being reabsorbed, your liver has to make more bile acids, which it does by using cholesterol from your blood.

This lowers the amount of cholesterol in your blood and reduces your risk of blood vessel disease. When colestyramine is prescribed for itching or diarrhoea, it helps to control your symptoms by reducing the amount of bile acids in your blood. Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken.

For these reasons, before you start taking colestyramine it is important that your doctor knows:. Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with colestyramine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

If you experience any other symptoms which you think may be due to the medicine, speak with your doctor or pharmacist for further advice.

Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.