How does femara work for infertility

Letrozole for infertility. Randy Morris M. Expand child menu Expand. Patient Resources Expand child menu Expand. Getting Started Expand child menu Expand.

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Methods for Testing Embryos Expand child menu Expand. In one study, researchers measured the effects of Clomiphene and Letrozole treatment on improving pregnancy rate, miscarriage rate, incidence rate of adverse events, and the number of dominant follicles for patients with unexplained infertility.

The results of the study showed that women treated with Letrozole displayed a significantly higher rate of clinical pregnancy as compared to those treated with Clomiphene. There was no statistical difference between the groups for the other fertility outcomes. Researchers concluded that Letrozole is at least as effective as Clomiphene for treating women with unexplained infertility. Researchers compared the efficacy of Letrozole and Clomiphene treatment on women with unexplained infertility in a randomized control trial.

More than double the percentage of women treated with Letrozole achieved pregnancy In addition to the higher pregnancy rate, the group treated with Letrozole also saw a statistically significant improvement in endometrial receptivity when measured by endometrial thickness and other indicators. Researchers concluded that Letrozole has a beneficial effect on the endometrium, which may improve implantation and pregnancy rates in women with unexplained infertility.

Letrozole is synonymous with the term ovulation Induction and can be used in conjunction with several different fertility treatments. Many fertility doctors have shifted to prescribing Letrozole in conjunction with the following treatments:. Timed intercourse is the simplest fertility treatment available. Letrozole is used during timed intercourse cycles to stimulate egg production and to induce ovulation.

During a timed intercourse cycle, doctors use ultrasound and blood work monitoring or even a home ovulation predictor kit to monitor follicular development and egg growth. By monitoring egg development and hormone levels, physicians are able to identify the window of time in which the woman is ovulating when fertilization is most likely to occur.

This allows couples to engage in sexual intercourse at the time, which gives them the best chance of getting pregnant. Research has shown that Letrozole treatment may be more effective than Clomid for patients with unexplained infertility who are undergoing timed intercourse treatment. In one study, patients treated with Letrozole showed statistically significant improvement in both endometrial thickness and follicular response when compared to the Clomid group.

The Letrozole group also had a significantly higher clinical pregnancy rate when compared to the Clomid group at Women whose infertility is caused by an ovulatory disorder are commonly prescribed Letrozole along with timed intercourse treatment. Similar to a timed intercourse cycle, Letrozole may be prescribed alongside IUI treatment to stimulate egg growth and to help time ovulation properly with the insemination. IUI treatment aims to increase the number of sperm that reach the uterus and then the fallopian tubes to increase the chance that successful fertilization will occur.

Letrozole is used to increase the number of eggs available for fertilization and to improve ovulation. When more eggs are produced, there are more targets available for the sperm to shoot at. As previously discussed, Letrozole can improve endometrial receptivity by increasing endometrial thickness and blood flow.

In one study, researchers measured the effects of endometrial thickness on pregnancy outcomes after IUI.

The results of the study showed a strong positive association between endometrial thickness and pregnancy outcome. The same study demonstrated advantages in several other areas:.

The risk of pregnancy loss, meanwhile, was more-or-less the same for both drugs Femara Similarly, a study published in PLoS One concluded that there was no significant difference in the overall rate of birth defect among children born to mothers who conceived naturally or those who used Femara or Clomid. Get diet and wellness tips to help your kids stay healthy and happy.

Letrozole, Gonadotropin, or Clomiphene for Unexplained Infertility. N Engl J Med. The use of high dose letrozole in ovulation induction and controlled ovarian hyperstimulation. Letrozole versus clomiphene for infertility in the polycystic ovary syndrome. Sharma, S; Ghosh, S. Your Privacy Rights. To change or withdraw your consent choices for VerywellFamily. At any time, you can update your settings through the "EU Privacy" link at the bottom of any page.

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Our site uses cookies so that we can remember you and understand how you use our site. For information about how we use cookies, please read our Privacy Policy. By browsing our website, you consent to our use of cookies and other tracking technologies. Apply Here Are You In? Become an Egg Donor Requirements. How to Take Letrozole for Fertility What is Letrozole? What does Letrozole do for fertility?

Is Letrozole better than Clomid? What are side effects of Letrozole? Side effects of Letrozole can include: Hot flashes Headaches Breast tenderness Fatigue Leg cramps Some women also find that infertility drugs that improve ovulation may also result in anxiety, mood swings, and irritability. What are the treatment protocols for taking Letrozole as a fertility treatment?